The Claisen condensation reaction is given by

Write Claisen condensation.

Ester gives nucleophilic addition reaction followed by elimination reaction with carbon nucleopile. When carbon nucleophile is of an ester then the reaction is known as Claisen condensation reaction. This reaction is also carried out between ester and a ketone. A suC Cessful Claisen condensation requires an ester with two alpha- hydrogens and an equivalent amount of base rather than a catalytic amount of base. Intramolecular Claisen condensation given diester is known as :

Ester gives nucleophilic addition reaction followed by elimination reaction with carbon nucleopile. When carbon nucleophile is of an ester then the reaction is known as Claisen condensation reaction. This reaction is also carried out between ester and a ketone. A suC Cessful Claisen condensation requires an ester with two alpha- hydrogens and an equivalent amount of base rather than a catalytic amount of base. Consider the given reaction CH_(3)-COOC_(2)H_(5)underset(C_(2)H_(5)OH)overset(C_(2)H_(5)ONa)rarr"enolate ion"underset("Claisen condensation")overset("ether(X)")rarr Product For the above reaction the most reactive ester is :