Among the statement given below, which statements /s is / are correct regarding the relationship between enzyme and substrate ?
I. Above a certain concentration of substrate , an enzyme reaches its maximum rate of reaction
II. Increasing the substrate concentration to a higher level doesn't reverse the effects of a competitive inhibitor.
III At high substrate concentration , a non competitive inhibitor no longer affects the enzyme activity .
IV. The higher the concentration of substrate the faster an enzyme can cataylse a reaction.