In agarose gel electrophoresis, DNA molecules are separated on the basic of their

Options

A. charge only
B. size only
C. charge to size ratio
D. All of these

Explanation

**Step-by-Step Solution:**

1. **Understanding Agarose Gel Electrophoresis**: Agarose gel electrophoresis is a technique used to separate DNA fragments based on their size. The gel acts as a molecular sieve.

2. **Role of Electric Field**: When an electric current is applied, DNA molecules, which are negatively charged due to their phosphate backbone, move towards the positive electrode. This movement is influenced by the size of the DNA fragments.

3. **Separation Based on Size**: The agarose gel has pores that allow smaller DNA fragments to move through more easily than larger ones. Therefore, smaller fragments travel further through the gel compared to larger fragments.

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