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Explain the role of allosteric site oin ...

Explain the role of allosteric site oin enzyme inhibition ?

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Some drugs do not bind to the active site of enzymes to inhibit their activities. These bind to a different site of enzyme. This binding of inhibitor (drug) changes the shape of the active site in such a way that substrate cannot recognise it.
The site different from active site of an enzyme where a drug molecule can bind is called the allosteric site.
Non-competative inhibitor changes the active site of enzyme after binding at allosteric site.
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