If the sequence of nitrogen bases of the coding strand of DNA in a transcription unit is `5'-A T G A A T G -3'`, the sequence of bases in its RNA transcript would be

Options

A. 5'- A U G A A U G - 3'
B. 5' - U A C U U A C - 3'
C. 5' - C A U U C A U - 3'
D. 5' - G U A A G U A - 3'

Explanation

To determine the sequence of bases in the RNA transcript from the given coding strand of DNA, follow these steps:

### Step-by-Step Solution:

1. **Identify the Coding Strand**: The coding strand of DNA is given as `5'-A T G A A T G -3'`.

2. **Transcription Process**: During transcription, the DNA coding strand is used to synthesize RNA. The RNA is complementary to the DNA template strand (which is the non-coding strand) but identical to the coding strand, except that thymine (T) in DNA is replaced by uracil (U) in RNA.

3. **Transcribe the DNA Sequence**:
- The coding strand is read from 5' to 3'.
- Replace thymine (T) with uracil (U) in the RNA transcript.

4. **Write the RNA Sequence**:
- The coding strand `5'-A T G A A T G -3'` translates to RNA as follows:
- A (Adenine) remains A (Adenine)
- T (Thymine) becomes U (Uracil)
- G (Guanine) remains G (Guanine)
- A (Adenine) remains A (Adenine)
- A (Adenine) remains A (Adenine)
- T (Thymine) becomes U (Uracil)
- G (Guanine) remains G (Guanine)

5. **Final RNA Sequence**: Therefore, the RNA transcript sequence is `5'-A U G A A U G -3'`.

### Final Answer:
The sequence of bases in the RNA transcript would be `5'-A U G A A U G -3'`.

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