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A single base mutation in a gene may not...

A single base mutation in a gene may not 'always' result in loss or gain of function. Do you think the statement is correct? Define your answer .

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The statement is correct. Because of degeneracy of codons, mutations at thrid base of codon, usually does not result into any change is phenotype . This is called silent mutations.
On other hand, if codon is changed in away that now it specifies another amino acid, it may other the protein function as it happens in cse of `beta`-globulin of heamoglobin protein. Where a subsittution of valine instead of glutamic acid causes change in its structure and function , and resulting into sickle-cell trait.
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NCERT EXEMPLAR ENGLISH-MOLECULAR BASIS INHERITANCE -Short Type Answer Questions
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