Potential difference across resting membrane is negatively charged. This is due to differential distribution of the following ions.

Options

A. `Na^(+) ` and `k^(+)` ions
B. `CO_(3)^(2-)` and `Cl^(-)` ions
C. `Ca^(+4)` and `Cl^(-)` ions
D. `Ca^(+4)` and `Cl^(-)` ions

Explanation

To solve the question regarding the negatively charged potential difference across the resting membrane due to the differential distribution of ions, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Resting Membrane Potential**:
- The resting membrane potential of a neuron is typically around -70 mV, indicating that the inside of the cell is more negatively charged compared to the outside.

2. **Identifying Key Ions**:
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