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Discuss briefly the role of nucleolus in...

Discuss briefly the role of nucleolus in the cells actively involved in protein synthesis.

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Nucleolus is the round, naked and a slightly irregular structure, which is attached to the chromatin at a specific region called as Nucleolar Organizer Region (NOR) Nucleolus was first discovered by Fontana ( 1781).

(i) Nucleolus is the chief site for the ribosomal RNA synthesis.
(ii) It is the centre for the formation of ribosome components.
(iii) It is the colloidal complex that fills the nucleus.
(iv) It combines rRNA with proteins to produce ribosomal sub-units. After their formation, the ribosomes sub-units pass out and get established in the cytoplasm.
(v) It also receive and store ribosomal proteins formed in the cytoplasm.
(vi) These ribosomal proteins formed are the sites for protein synthesis in the cell.
(vii) Nucleolus is essential for spindle formation during nuclear division.
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