Which type of immune reSQPonse is reSQPonsible for the rejection of tissue/organs in the patient's body post tranSQPlantation ?

Options

A. auto -immune reSQPonse
B. humoral immune reSQPonse
C. physiologica immune reSQPonse
D. cell-mediated immune reSQPonse

Explanation

To answer the question regarding which type of immune response is responsible for the rejection of tissue/organs in a patient's body post-transplantation, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding Transplantation**:
- Transplantation involves transferring tissues or organs from one individual to another. This can be from a donor to a recipient.

2. **Immune System Function**:
- The immune system has the ability to distinguish between "self" (the body’s own cells) and "non-self" (foreign cells or tissues). This is crucial for maintaining health and preventing infections.

3. **Rejection Mechanism**:
- When a foreign tissue or organ is introduced into the body, the immune system recognizes it as non-self. This triggers an immune response aimed at rejecting the foreign material.

4. **Types of Immune Response**:
- There are two main types of immune responses: humoral (mediated by antibodies) and cell-mediated (involving T-cells).

5. **Cell-Mediated Immune Response**:
- The rejection of transplanted tissues or organs is primarily due to the cell-mediated immune response. T-cells, particularly cytotoxic T-cells, play a significant role in identifying and attacking the foreign cells.

6. **Importance of Matching**:
- To minimize rejection, tissue matching (ensuring compatibility between donor and recipient) and blood group matching are essential before transplantation.

7. **Conclusion**:
- The type of immune response responsible for the rejection of tissue/organs post-transplantation is the **cell-mediated immune response**.

### Final Answer:
The correct answer is the **cell-mediated immune response**.

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