Holoenzyme is the complete enzyme consisting of an apoenzyme and a co-factor. Select the option that correctly identifies the nature of apoenzyme and co-factor.

Options

A. `{:("Apoenzyme","Co-factor"),("Protein" ,"Non-protein"):}`
B. `{:("Apoenzyme","Co-factor"),("Non-protein" ,"Protein"):}`
C. `{:("Apoenzyme","Co-factor"),("Protein" ,"Protein"):}`
D. `{:("Apoenzyme","Co-factor"),("Non-protein" ,"Non-protein"):}`

Explanation

To solve the question regarding the nature of apoenzyme and co-factor in a holoenzyme, let's break it down step by step:

### Step-by-Step Solution:

1. **Understanding Holoenzyme**:
- A holoenzyme is defined as the complete, active form of an enzyme. It consists of two main components: an apoenzyme and a co-factor.

2. **Identifying Apoenzyme**:
- The apoenzyme is the protein part of the holoenzyme. It is the part that provides the specific structure and catalytic activity of the enzyme.

3. **Identifying Co-factor**:
- The co-factor is the non-protein part of the holoenzyme. It can be further categorized into two types:
- **Inorganic co-factors**: These include metal ions such as zinc (Zn²⁺), magnesium (Mg²⁺), etc.
- **Organic co-factors**: Often referred to as coenzymes, these are organic molecules that assist in enzyme activity, such as vitamins.

4. **Conclusion**:
- Based on the definitions:
- The apoenzyme is a **protein**.
- The co-factor is a **non-protein** component (which can be either inorganic or organic).

5. **Correct Option**:
- Therefore, the correct option that identifies the nature of apoenzyme and co-factor is: **Apoenzyme is protein and co-factor is non-protein**.