Read the given paragraph with few blanks.
Prosthetic groups are `underline((i))` compunds distinguished from other co-factors in being `underline((ii))` bound to the apoenzyme. For example, in peroxidase and `underline((iii))` which catalyse the breakdown of hydrogen peroxide to water and `underline ((iv)),underline((v))` is the prosthetic group.
Select the option that correctly fills blanks in the above paragraph.

Options

A. a) `{:(column-i,column-ii,column-iii,column-iv,column-v),("organic" ,"tightly" ,"catalase" ,"oxygen", "haem"):}`
B. b) `{:(column-i,column-ii,column-iii,column-iv,column-v),("inorganic" ,"loosely" ,"catalase" ,"hydrogen", "haem"):}`
C. c) `{:(column-i,column-ii,column-iii,column-iv,column-v),("inorganic" ,"tightly" ,"isomerase" ,"hydrogen", "haem"):}`
D. d) `{:(column-i,column-ii,column-iii,column-iv,column-v),("organic" ,"loosely" ,"isomerase" ,"oxygen", "haem"):}`

Answer

To fill in the blanks in the given paragraph, we need to identify the correct terms based on the information provided in the video transcript. Here’s the step-by-step solution:

1. **Blank (i)**: The term that describes prosthetic groups is "organic" because prosthetic groups can be organic or inorganic compounds, but in this context, they are specifically referring to organic compounds.
- **Hint**: Think about the nature of prosthetic groups and what they are primarily composed of.

2. **Blank (ii)**: Prosthetic groups are "tightly" bound to the apoenzyme. This distinguishes them from other co-factors, which may not bind as firmly.
- **Hint**: Consider how prosthetic groups interact with enzymes compared to other types of co-factors.

3. **Blank (iii)**: The enzyme that catalyzes the breakdown of hydrogen peroxide is "catalase." This enzyme works alongside peroxidase in this reaction.
- **Hint**: Recall the enzymes involved in the breakdown of hydrogen peroxide.

4. **Blank (iv)**: The product of the breakdown of hydrogen peroxide includes "water" and "oxygen." Therefore, the fourth blank will be "water."
- **Hint**: Think about the chemical reaction that occurs when hydrogen peroxide decomposes.

5. **Blank (v)**: The prosthetic group involved in this reaction is "heme." Heme is an organic compound that contains iron and is a component of hemoglobin.
- **Hint**: Identify the specific prosthetic group associated with the enzymes mentioned.

Now, putting it all together, we can fill in the blanks as follows:

Prosthetic groups are **(i) organic** compounds distinguished from other co-factors in being **(ii) tightly** bound to the apoenzyme. For example, in peroxidase and **(iii) catalase** which catalyze the breakdown of hydrogen peroxide to water and **(iv) oxygen**, **(v) heme** is the prosthetic group.

Thus, the correct option that fills the blanks is:
- (i) organic
- (ii) tightly
- (iii) catalase
- (iv) water
- (v) heme

### Summary of the Correct Answers:
1. (i) organic
2. (ii) tightly
3. (iii) catalase
4. (iv) water
5. (v) heme