Synthesis of histone proteins occurs in

Options

A. `G_(1)` phase
B. interphase
C. anaphase
D. `G_(0)` phase.

Explanation

To answer the question regarding the synthesis of histone proteins, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Cell Cycle**: The cell cycle consists of several phases: G1 (Gap 1), S (Synthesis), G2 (Gap 2), and M (Mitosis). Interphase includes G1, S, and G2 phases.

2. **Identify the S Phase**: The S phase is specifically known as the synthesis phase where DNA replication occurs. During this phase, the amount of DNA in the cell doubles, but the number of chromosomes remains the same.

3. **Histone Protein Synthesis**: Histone proteins are essential for DNA packaging and are synthesized during the S phase because they are required for the newly replicated DNA.

4. **Choose the Correct Option**: Since the S phase is part of interphase, and histone synthesis occurs during the S phase, we can conclude that the synthesis of histone proteins occurs during interphase.

5. **Final Answer**: Therefore, the correct answer to the question is that the synthesis of histone proteins occurs in **interphase**.