____ is characterised by all the chromosomes coming to lie at the equator, with one chromatid connected by its kinetochore to spindle fibres from one pole and its sister chromatid connected by its kinetochore to spindle fibres from the opposite pole.

Options

A. Prophase
B. Metaphase
C. Anaphase
D. Telophase

Answer

To answer the question, we need to identify the stage of cell division characterized by specific arrangements of chromosomes and their connections to spindle fibers. Here’s a step-by-step solution:

### Step-by-Step Solution:

1. **Understanding the Question**: The question describes a stage in cell division where all chromosomes align at the equator of the cell. Each chromosome consists of two sister chromatids, which are connected to spindle fibers from opposite poles.

2. **Identifying the Key Features**:
- Chromosomes are at the equatorial plate.
- Each chromatid is connected to spindle fibers from opposite poles via kinetochores.

3. **Recalling Cell Division Stages**: The stages of cell division include:
- Prophase
- Metaphase
- Anaphase
- Telophase

4. **Analyzing Each Stage**:
- **Prophase**: Chromatin condenses into visible chromosomes, but they are not yet aligned at the equator.
- **Metaphase**: This is the stage where chromosomes align at the equatorial plate, and each chromatid is attached to spindle fibers from opposite poles.
- **Anaphase**: Sister chromatids separate and move toward opposite poles, which does not match the description given.
- **Telophase**: The cell begins to divide, and chromosomes de-condense, which also does not match the description.

5. **Conclusion**: Based on the analysis, the stage characterized by all chromosomes lying at the equator with each chromatid connected to spindle fibers from opposite poles is **Metaphase**.

### Final Answer:
**Metaphase**

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