Match the column I with column II and select the correct option from the given codes.
`{:("Column I","Column II"),("Disintegration of nuclear membrane",(i)"Anaphase"),("Appearance of nucleoulus",(ii)"Prophase"),("Division of centromere",(iii)"Telophase"),("Replication of DNA",(iv)"S-phase"):}`

Options

A. ii,iii,i,iv
B. ii,iii,iv,i
C. iii,ii,i,iv
D. iii,ii,iv,i

Answer

To solve the matching question between Column I and Column II, we need to analyze each item in Column I and identify the corresponding phase from Column II.

### Step-by-Step Solution:

1. **Disintegration of nuclear membrane**:
- This event occurs during **Prophase**. In this phase, the nuclear membrane breaks down, allowing the chromosomes to condense and become visible.
- **Match**: Disintegration of nuclear membrane → Prophase (ii)

2. **Appearance of nucleolus**:
- The nucleolus reappears during **Telophase**. After the chromosomes have been separated and the nuclear membrane begins to reform, the nucleolus becomes visible again.
- **Match**: Appearance of nucleolus → Telophase (iii)

3. **Division of centromere**:
- The division of the centromere occurs during **Anaphase**. In this phase, the centromeres split, allowing the sister chromatids to move towards opposite poles of the cell.
- **Match**: Division of centromere → Anaphase (i)

4. **Replication of DNA**:
- DNA replication occurs during the **S-phase** (Synthesis phase) of interphase. This is when the genetic material is duplicated in preparation for cell division.
- **Match**: Replication of DNA → S-phase (iv)

### Final Matches:
- Disintegration of nuclear membrane → Prophase (ii)
- Appearance of nucleolus → Telophase (iii)
- Division of centromere → Anaphase (i)
- Replication of DNA → S-phase (iv)

### Correct Option:
Based on the matches, the correct option is:
1. Disintegration of nuclear membrane → Prophase (ii)
2. Appearance of nucleolus → Telophase (iii)
3. Division of centromere → Anaphase (i)
4. Replication of DNA → S-phase (iv)