Assertion: Reductive amination involves the transfer of amino group from one amino acid to the keto group of a keto acid.
Reason: In reductive amination, transfer of `NH_(2)` from glutamic acid takes place.

Options

A. If both assertion and reason are true and reason is the correct explanation of assertion
B. if both assertion and reason are true but reason is not the correct explanation of assertion
C. if assertion is true but reason is false
D. if both assertion and reason are false

Explanation

To analyze the given assertion and reason, we can break down the solution into the following steps:

### Step-by-Step Solution:

1. **Understanding the Assertion**:
- The assertion states that "Reductive amination involves the transfer of amino group from one amino acid to the keto group of a keto acid."
- In reductive amination, the process typically involves the combination of ammonia with a keto acid to form an amino acid, not the transfer of an amino group from one amino acid.

2. **Understanding the Reason**:
- The reason states that "In reductive amination, transfer of NH2 from glutamic acid takes place."
- This statement is misleading because the transfer of the amino group from glutamic acid occurs in transamination, not reductive amination.

3. **Differentiating Reductive Amination and Transamination**:
- Reductive amination involves the direct combination of ammonia with a keto acid (like alpha-ketoglutarate) to form an amino acid, facilitated by enzymes such as glutamate dehydrogenase.
- Transamination, on the other hand, is the process where an amino group is transferred from one amino acid (such as glutamic acid) to a keto acid, forming a new amino acid and a new keto acid.

4. **Evaluating the Truth of the Statements**:
- Since the assertion incorrectly describes reductive amination and the reason incorrectly describes the process involved in reductive amination, both statements are false.

5. **Conclusion**:
- Therefore, the correct answer is that both the assertion and reason are false.

### Final Answer:
Both assertion and reason are false.

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