Coagulation will not be affected in the absence of factor

Options

A. `VII`
B. `XII`
C. `VIII`
D. `VI`

Explanation

### Step-by-Step Solution:

1. **Understanding Blood Coagulation**:
- Blood coagulation is the process by which blood changes from a liquid to a gel, forming a blood clot. This is crucial for stopping bleeding when a blood vessel is injured.

2. **Identifying Coagulation Factors**:
- Several factors are involved in the coagulation process. Key factors include:
- **Factor VII (7)**: Known as the stable factor or pro-convertant, it is essential for coagulation.
- **Factor XII (12)**: Known as the Hageman factor, it plays a role in the coagulation cascade.
- **Factor VIII (8)**: Known as the antihemophilic factor, it is critical for normal clotting.
- **Factor VI (6)**: This factor is not essential for coagulation and is involved in the ionization of calcium.

3. **Evaluating the Options**:
- The question asks which factor's absence will not affect coagulation.
- **Option 1**: Factor VII - Its absence will affect coagulation. (Incorrect)
- **Option 2**: Factor XII - Its absence will also affect coagulation. (Incorrect)
- **Option 3**: Factor VIII - Its absence will affect coagulation. (Incorrect)
- **Option 4**: Factor VI - Its absence will not significantly affect coagulation as it is not essential. (Correct)

4. **Conclusion**:
- The correct answer is **Factor VI (6)**, as its absence does not significantly impact the coagulation process.