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Consider the first reaction of TCA cycle...

Consider the first reaction of TCA cycle.
Acetyl `CoA + OA A +H_(2)O overset("Citrate")underset("synthase")rarr A + CoA` What is true about compound A?

A

First product of TCA cycle

B

Tricarboxylic acid and six carbon compound

C

It undergoes reorganisation in the presence of enzyme aconitase to form cis-aconitate

D

All of these

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The correct Answer is:
To solve the question regarding compound A in the first reaction of the TCA cycle, we need to analyze the reaction step by step. ### Step-by-Step Solution: 1. **Identify the Reactants**: The reaction given is: \[ \text{Acetyl CoA} + \text{Oxaloacetic Acid} + \text{H}_2\text{O} \overset{\text{Citrate Synthase}}{\rightarrow} A + \text{CoA} \] Here, the reactants are Acetyl CoA and Oxaloacetic Acid, along with water. 2. **Understand the Role of Enzyme**: The enzyme involved in this reaction is Citrate Synthase. This enzyme catalyzes the condensation reaction between Acetyl CoA and Oxaloacetic Acid. 3. **Determine the Product**: The product A formed from this reaction is Citrate. The reaction involves the combination of the two carbon atoms from Acetyl CoA and the four carbon atoms from Oxaloacetic Acid, resulting in a six-carbon compound, which is Citrate. 4. **Citrate Structure**: The structure of Citrate can be represented as: \[ \text{C}_6\text{H}_5\text{O}_7 \] It contains three carboxyl groups (-COOH), making it a tricarboxylic acid. 5. **Confirm Characteristics of Compound A**: - **First Product of TCA Cycle**: Citrate is indeed the first product formed in the TCA cycle. - **Six-Carbon Compound**: Citrate is a six-carbon compound. - **Undergoes Further Reactions**: Citrate can undergo further reactions, such as conversion to cis-aconitate in the presence of the enzyme aconitase. 6. **Conclusion**: Based on the above analysis, we can conclude that compound A is Citrate, and the statements regarding it being the first product of the TCA cycle, being a six-carbon compound, and undergoing further reactions are all true. ### Final Answer: The correct answer is that all statements about compound A (Citrate) are true. ---

To solve the question regarding compound A in the first reaction of the TCA cycle, we need to analyze the reaction step by step. ### Step-by-Step Solution: 1. **Identify the Reactants**: The reaction given is: \[ \text{Acetyl CoA} + \text{Oxaloacetic Acid} + \text{H}_2\text{O} \overset{\text{Citrate Synthase}}{\rightarrow} A + \text{CoA} ...
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