Juxtaglomerular apparatus is made up of

Explanation

**Step-by-Step Solution:**

1. **Understanding the Juxtaglomerular Apparatus (JGA):**
- The Juxtaglomerular Apparatus is a specialized structure located at the junction of the distal convoluted tubule (DCT) and the glomerulus in the nephron of the kidney.

2. **Components of the JGA:**
- The JGA is primarily made up of three types of cells:
- **Juxtaglomerular Cells:** These cells are located in the wall of the afferent arteriole, which supplies blood to the glomerulus. They are responsible for the secretion of renin, an enzyme that plays a crucial role in regulating blood pressure.
- **Macula Densa Cells:** These cells are part of the DCT and are sensitive to sodium chloride concentration. They help regulate glomerular filtration rate and blood pressure by signaling the juxtaglomerular cells to release renin when sodium levels are low.
- **Extraglomerular Mesangial Cells:** Also known as lacis cells, these cells are located between the afferent and efferent arterioles and the glomerulus. They provide structural support and may play a role in the regulation of glomerular filtration.

3. **Conclusion:**
- Therefore, the Juxtaglomerular Apparatus is made up of:
- Juxtaglomerular cells
- Macula densa cells
- Extraglomerular mesangial cells

**Final Answer:** The Juxtaglomerular Apparatus is made up of juxtaglomerular cells, macula densa cells, and extraglomerular mesangial cells.

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