Which of the following sequences is correct regarding regulation of kidney function?

Options

A. a) An excess loss of water from body `to` Hypothalamus `to` Osmoreceptors `to` Neurohypohysis `to` ADH `to`Increases water permeability of DCT and CT `to` prevention of diuresis
B. b) An excess loss of fluid from body `to` Osmoreceptors `to` Hypothalamus `to` Neurohypophysis `to` ADH `to` increases water permeability of DCT and CT`to`Prevention of diuresis
C. c) An execss loss of fluid from body `to` Osmoreceptors `to` Hypothalamus `to` Neurohypophysis `to` aldosterone `to` water permeability of DCT and CT increases `to` Prevetion of diuresis
D. d) An excess loss of fluid from body `to` Osmoreceptors `to` Hypothalamus `to` Adenohypophysis `to` ADH`to` Increases water permeability of DCT and CT `to` Prevention of diuresis

Answer

### Step-by-Step Solution:

1. **Understanding the Problem**: The question asks for the correct sequence of events regarding the regulation of kidney function, particularly in response to water loss from the body.

2. **Initial Trigger**: When there is a loss of water from the body, it leads to changes in blood volume and ionic concentration. This is the first step in the sequence.

3. **Activation of Osmoreceptors**: The changes in body fluid volume and ionic concentration stimulate osmoreceptors in the body. This is the second step.

4. **Stimulation of Hypothalamus**: The osmoreceptors then send signals to the hypothalamus, which is the third step in the sequence.

5. **Release of ADH**: The hypothalamus stimulates the neurohypophysis (posterior pituitary gland) to release Antidiuretic Hormone (ADH). This is the fourth step.

6. **Action of ADH**: ADH increases the reabsorption of water in the nephron, specifically in the proximal convoluted tubule (PCT) and distal convoluted tubule (DCT). This is the fifth step.

7. **Prevention of Diuresis**: By increasing water reabsorption, ADH prevents diuresis (loss of water), which is the final step in the sequence.

8. **Conclusion**: The correct sequence is:
- Loss of water → Stimulates osmoreceptors → Stimulates hypothalamus → Stimulates neurohypophysis → Releases ADH → Increases water reabsorption in PCT and DCT → Prevents diuresis.