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Assertion: Stimulation of renin secretio...

Assertion: Stimulation of renin secretion will increase the volume of the extracellular fluid (ECF).
Reason: The increased ECF occurs due to decreased active reabsorption of `Na^(+)`

A

If both assertion and reason are true and reason is the correct explanation of assertion

B

if both assertion and reason are true but reason is not the correct explanation of assertion.

C

if assertion is true but reason is false

D

if both assertion and reason are false.

Text Solution

AI Generated Solution

The correct Answer is:
To analyze the given assertion and reason, we will break it down step by step. ### Step 1: Understanding the Assertion The assertion states that "stimulation of renin secretion will increase the volume of the extracellular fluid (ECF)." - **Explanation**: Renin is an enzyme secreted by the kidneys in response to low blood pressure or low sodium levels. When renin is released, it activates a cascade of events that leads to the production of angiotensin II, which causes vasoconstriction and stimulates the adrenal glands to release aldosterone. Aldosterone promotes sodium reabsorption in the kidneys, which in turn increases water retention, leading to an increase in the volume of ECF. ### Step 2: Understanding the Reason The reason states that "the increased ECF occurs due to decreased active reabsorption of Na+." - **Explanation**: This statement is incorrect. Increased ECF volume is actually due to increased active reabsorption of sodium (Na+). When sodium is reabsorbed, water follows due to osmosis, leading to an increase in the volume of ECF. Therefore, the assertion is true, but the reason is false. ### Step 3: Conclusion Based on the analysis: - The assertion is true: Stimulation of renin secretion does increase the volume of ECF. - The reason is false: Increased ECF occurs due to increased, not decreased, active reabsorption of Na+. ### Final Answer The correct option is: "If the assertion is true, the reason is false."

To analyze the given assertion and reason, we will break it down step by step. ### Step 1: Understanding the Assertion The assertion states that "stimulation of renin secretion will increase the volume of the extracellular fluid (ECF)." - **Explanation**: Renin is an enzyme secreted by the kidneys in response to low blood pressure or low sodium levels. When renin is released, it activates a cascade of events that leads to the production of angiotensin II, which causes vasoconstriction and stimulates the adrenal glands to release aldosterone. Aldosterone promotes sodium reabsorption in the kidneys, which in turn increases water retention, leading to an increase in the volume of ECF. ### Step 2: Understanding the Reason The reason states that "the increased ECF occurs due to decreased active reabsorption of Na+." ...
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