Besides corticotropin releasing hormone (CRH) which other hormone also stimulates the release of adrenocorticotropic hormone (ACTH) ?

Options

A. Glucagon
B. Insulin
C. Aldosterone
D. Epinephrine

Explanation

To answer the question, "Besides corticotropin releasing hormone (CRH), which other hormone also stimulates the release of adrenocorticotropic hormone (ACTH)?", we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Role of CRH**:
- Corticotropin releasing hormone (CRH) is primarily responsible for stimulating the release of adrenocorticotropic hormone (ACTH) from the anterior pituitary gland.

2. **Identifying Other Hormones**:
- The question asks for another hormone that can also stimulate the release of ACTH. We need to analyze the options provided: glucagon, insulin, aldosterone, and epinephrine.

3. **Analyzing Each Option**:
- **Glucagon**: This hormone primarily regulates blood glucose levels and does not have a direct role in stimulating ACTH release.
- **Insulin**: This hormone is involved in lowering blood sugar levels and does not stimulate ACTH release.
- **Aldosterone**: This hormone is involved in regulating sodium and potassium levels and does not stimulate ACTH release.
- **Epinephrine (Adrenaline)**: This hormone is involved in the body's fight-or-flight response and has been shown to stimulate the hypothalamus, which can lead to increased secretion of CRH and subsequently ACTH.

4. **Conclusion**:
- Based on the analysis, the hormone that also stimulates the release of ACTH, besides CRH, is **epinephrine**. Therefore, the correct answer is option D: epinephrine.

### Final Answer:
**Epinephrine (Adrenaline)** is the hormone that also stimulates the release of adrenocorticotropic hormone (ACTH) besides corticotropin releasing hormone (CRH).

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