Which one of the following is not the function of insulin?

Options

A. Increaes the permeability of cell membrane to glucose
B. Increases the oxidation of glucose in the cells
C. Initiates the conversion of glycogen to glucose
D. Initiates the formation of hepatic glycogen from excess of glucose

Explanation

To determine which of the following statements is not a function of insulin, we will analyze each statement one by one:

1. **Increases the permeability of cell membrane to glucose**:
- Insulin facilitates the uptake of glucose by increasing the permeability of the cell membrane to glucose. This means that insulin helps cells absorb more glucose from the bloodstream.
- **Conclusion**: This statement is correct.

2. **Increases the oxidation of glucose in the cells**:
- Insulin promotes the oxidation of glucose, which is a process where glucose is broken down to produce energy. This is one of the key roles of insulin in regulating blood sugar levels.
- **Conclusion**: This statement is also correct.

3. **Initiates the conversion of glycogen to glucose**:
- This statement is incorrect. Insulin does not initiate the conversion of glycogen to glucose; instead, it promotes the conversion of glucose into glycogen for storage (glycogenesis). The conversion of glycogen to glucose (glycogenolysis) is stimulated by glucagon, not insulin.
- **Conclusion**: This statement is incorrect.

4. **Initiates the formation of hepatic glycogen from excess of glucose**:
- Insulin facilitates the conversion of excess glucose into glycogen in the liver, which is known as glycogenesis. This is indeed a function of insulin.
- **Conclusion**: This statement is correct.

Based on the analysis, the statement that is not a function of insulin is:

**Answer**: Initiates the conversion of glycogen to glucose.

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