Which of the following is the correct pairing regarding a specific disorder of muscular or skeletal system ?

Options

A. Muscular dystrophy - Age related shortening of muscles
B. Osteoporosis - Decrases in bone mass and higher chances of fractures with advancing age
C. Myasthenia - Autoimmune disorder which inhibits slididng of myosin filaments
D. Gout - Inflammation of joint due to extra deposition of calcium

Answer

To solve the question regarding the correct pairing of a disorder of the muscular or skeletal system, we will analyze each option provided in the question step by step.

### Step-by-Step Solution:

1. **Evaluate Muscular Dystrophy**:
- **Claim**: Muscular dystrophy is an age-related shortening of muscles.
- **Analysis**: Muscular dystrophy is indeed a disorder of the muscular system, but it is not age-related. It is primarily a genetic disorder that leads to the degeneration of muscle tissue.
- **Conclusion**: This pairing is incorrect.

2. **Evaluate Osteoporosis**:
- **Claim**: Osteoporosis is a decrease in bone mass and higher chances of fractures with advancing age.
- **Analysis**: Osteoporosis is characterized by a decrease in bone density, which indeed increases the risk of fractures. This condition is commonly associated with aging due to hormonal changes, particularly a decrease in estrogen levels.
- **Conclusion**: This pairing is correct.

3. **Evaluate Myasthenia Gravis**:
- **Claim**: Myasthenia gravis is an autoimmune disorder which inhibits sliding of myosin filaments.
- **Analysis**: Myasthenia gravis is an autoimmune disorder that affects the neuromuscular junction, leading to muscle weakness and fatigue. It does not inhibit the sliding of myosin filaments; rather, it affects the communication between nerves and muscles. The sliding mechanism involves actin filaments, not myosin.
- **Conclusion**: This pairing is incorrect.

4. **Evaluate Gout**:
- **Claim**: Gout is inflammation of joints due to extra deposition of calcium.
- **Analysis**: Gout is indeed an inflammatory condition of the joints, but it is caused by the deposition of uric acid crystals, not calcium. Calcium is important for bone structure but is not the cause of gout.
- **Conclusion**: This pairing is incorrect.

### Final Answer:
The only correct pairing regarding a specific disorder of the muscular or skeletal system is:
- **Osteoporosis**: Decrease in bone mass and higher chances of fractures with advancing age.