Limbalances of certain hormones, deficiencies of calcium and vitamin D are the major causative factors of

Options

A. rheumatoid arthritis
B. osteoporosis
C. osteoarthritis
D. gouty arthritis.

Explanation

**Step-by-Step Solution:**

1. **Identify the Factors**: The question mentions "imbalance of certain hormones," "deficiencies of calcium," and "vitamin D." We need to find a disease associated with these factors.

2. **Understand the Options**: The options provided are rheumatoid arthritis, osteoporosis, osteoarthritis, and gouty arthritis. All these conditions are related to the skeletal system and involve joint issues.

3. **Focus on Hormonal Imbalance**: Osteoporosis is known to be significantly influenced by hormonal changes, particularly in post-menopausal women where estrogen levels drop. This hormonal imbalance leads to a decrease in bone density.

4. **Consider Nutritional Deficiencies**: Calcium and vitamin D are crucial for bone health. A deficiency in these nutrients can lead to weakened bones. Vitamin D is essential for calcium absorption in the body.

5. **Connect the Dots**: Given that osteoporosis is characterized by decreased bone density and is influenced by hormonal changes and nutritional deficiencies, it aligns perfectly with the factors mentioned in the question.

6. **Conclusion**: Therefore, the disease caused by the imbalance of certain hormones, deficiencies of calcium, and vitamin D is **osteoporosis**.

---