Select the incorrect statement regarding pedigree analysis

Options

A. Solid symbols show unaffected individuals
B. Proband is the person from which case history starts
C. It is useful for genetic counsellors
D. It is an alalysis of traits in several generations of a family

Explanation

**Step-by-Step Solution:**

1. **Understanding Pedigree Analysis**:
- Pedigree analysis is a method used to study the inheritance of traits in a family across generations. It helps in understanding how traits are passed from parents to offspring.

2. **Evaluating the Statements**:
- **Option A**: "Solid symbols show unaffected individuals."
- This statement is incorrect. In pedigree charts, solid symbols represent affected individuals, while open symbols represent unaffected individuals.

- **Option B**: "Proband is the person from which case history starts."
- This statement is correct. The proband is indeed the individual in a pedigree from whom the study or case history begins.

- **Option C**: "It is useful for genetic counselors."
- This statement is also correct. Pedigree analysis is a valuable tool for genetic counselors to assess the risk of genetic disorders in families.

- **Option D**: "It is an analysis of traits in several generations of a family."
- This statement is correct as well. Pedigree analysis examines traits over multiple generations to understand inheritance patterns.

3. **Identifying the Incorrect Statement**:
- After evaluating all the options, it is clear that **Option A** is the incorrect statement regarding pedigree analysis.

**Final Answer**: The incorrect statement regarding pedigree analysis is **Option A**: "Solid symbols show unaffected individuals."

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