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The possibility of a female becoming hae...

The possibility of a female becoming haemophilic is extremely rare because mother of such a female has to be at least `overset("(i)") "____"` and father should be `overset("(ii)") "____"`

A

(i) haemophilic, (ii) carrier

B

(i) carrier, (ii) haemophilic

C

(i) haemophilic, (ii) normal

D

(i) haemophilic, (ii) haemophilic

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To solve the question regarding the rarity of a female becoming hemophilic, we need to understand the genetics behind hemophilia, which is an X-linked recessive disorder. Here’s a step-by-step breakdown of the solution: ### Step 1: Understanding Hemophilia Hemophilia is a genetic disorder caused by the deficiency of clotting factors in the blood, leading to excessive bleeding. It is primarily inherited in an X-linked recessive manner. **Hint:** Recall that X-linked recessive disorders predominantly affect males, as they have only one X chromosome. ### Step 2: Genetic Composition of Males and Females - Males have one X and one Y chromosome (XY). - Females have two X chromosomes (XX). **Hint:** Remember that males express the trait if their single X chromosome carries the hemophilia gene, while females need both X chromosomes to carry the gene to express the disorder. ### Step 3: Conditions for a Female to be Hemophilic For a female to be hemophilic, she must inherit two copies of the hemophilia allele (one from each parent). This means: - The mother must contribute one X chromosome with the hemophilia gene. - The father must provide the other X chromosome, which will also carry the hemophilia gene since he has only one X chromosome. **Hint:** Think about how traits are inherited from both parents and the necessity of receiving the same trait from both sides for females. ### Step 4: Determining the Mother's Genotype For the mother to pass on the hemophilia gene, she must be at least a carrier (X^hX), where X^h represents the X chromosome with the hemophilia allele. If she were normal (XX), she could not pass on the hemophilia allele. **Hint:** A carrier has one normal X chromosome and one affected X chromosome, allowing her to pass on the disorder without being affected herself. ### Step 5: Determining the Father's Genotype The father must be hemophilic (X^hY) because he has only one X chromosome. If he were normal (XY), he would not be able to pass on the hemophilia allele. **Hint:** Since males have only one X chromosome, if that X carries the hemophilia gene, they will express the disorder. ### Final Answer Thus, the answers to fill in the blanks are: - (i) **carrier** (the mother must be a carrier) - (ii) **hemophilic** (the father must be hemophilic) ### Summary The possibility of a female becoming hemophilic is extremely rare because the mother of such a female has to be at least **carrier** and the father should be **hemophilic**.

To solve the question regarding the rarity of a female becoming hemophilic, we need to understand the genetics behind hemophilia, which is an X-linked recessive disorder. Here’s a step-by-step breakdown of the solution: ### Step 1: Understanding Hemophilia Hemophilia is a genetic disorder caused by the deficiency of clotting factors in the blood, leading to excessive bleeding. It is primarily inherited in an X-linked recessive manner. **Hint:** Recall that X-linked recessive disorders predominantly affect males, as they have only one X chromosome. ### Step 2: Genetic Composition of Males and Females ...
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Explain the pattern oftinheritance of haemophilia in humans. Why is the possibility of a human female becoming haemophilic extremely rare ? Explain.

Explain the pattern of inheritance of haemophilia in humans. Why is the possibility of a human female becoming a haemophilic is extremely rare ? Explain.

NCERT FINGERTIPS ENGLISH-PRINCIPLES OF INHERITANCE & VARIATION-Principles Of Inheritance & Variation
  1. "" is an example of X-linked recessive trait

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  2. If a haemophilic man marries a carrier woman than which of the followi...

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  3. The possibility of a female becoming haemophilic is extremely rare bec...

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  4. Result of a cross between a normal homozygous female and a haemophili...

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  5. Father of a child is colourblind and mother is carrier for colourblin...

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  6. A coloured man (X^(c)Y) marries a woman who is carrier for haemophilia...

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  7. A marriage between a colourblind man and a normal woman produces

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  8. Red green colourblindness is a sex linked trait. Which of the given st...

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  9. The disease sickle-cell anaemia is caused by the substitution of over...

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  10. Study the given pedigree chart for sickle-cell anaemia and select the ...

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  11. Refer to the give figure The shape of RBCs under oxygen tension ...

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  12. An individual affected by phenylketonuria lacks an enzyme that convert...

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  13. Which of the following is not a example of recessive autosomal disease...

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  14. If both parents are carriers for thalassaemia, which is an autosomal r...

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  15. Select the disease which is caused by recessive autosomal genes when p...

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  16. In this disease, there occurs a failure of chloride ion transport mech...

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  17. Match column I with column II and select the correct option from th...

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  18. Which of the following trait is controlled by dominant autosomal genes...

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  19. Refer the given statements (i) Incomplete or mosaic inheritance is ...

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  20. Failure of segregation of chromatids during cell division results in t...

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