Match column I with column II and select the correct option from the given codes
`{:(,"Column I",,"Column II"),("A.","Sickle cell anaemia","(i)","7th chromosome"),("B.","Pheylketonuria","(ii)","4th chromosome"),("C.","Cystic fibrosis","(iii)","11th chromosome"),("D.","Huntington's disease","(iv)","X-chromosome"),("E.","Colourblindness","(v)","12th chromosome"):}`

Options

A. A-(iii),B-(v),C-(ii),D-(i),E-(iv)
B. A-(iii),B-(v),C-(i),D-(ii),E-(iv)
C. A-(v),B-(iv),C-(ii),D-(iii),E-(i)
D. A-(iv),B-(ii),C-(iii),D-(i),E-(v)

Answer

To solve the problem of matching Column I with Column II, we will analyze each condition in Column I and identify the corresponding chromosome from Column II.

### Step-by-Step Solution:

1. **Identify the condition in Column I: Sickle Cell Anaemia (A)**
- Sickle cell anaemia is an autosomal recessive disorder caused by a mutation in the HBB gene, which is located on chromosome 11.
- **Match:** A → (iii) 11th chromosome

2. **Identify the condition in Column I: Phenylketonuria (B)**
- Phenylketonuria (PKU) is a metabolic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase, which is linked to chromosome 12.
- **Match:** B → (v) 12th chromosome

3. **Identify the condition in Column I: Cystic Fibrosis (C)**
- Cystic fibrosis is an autosomal recessive disorder caused by mutations in the CFTR gene, which is located on chromosome 7.
- **Match:** C → (ii) 7th chromosome

4. **Identify the condition in Column I: Huntington's Disease (D)**
- Huntington's disease is an autosomal dominant disorder caused by a mutation in the HTT gene, which is located on chromosome 4.
- **Match:** D → (i) 4th chromosome

5. **Identify the condition in Column I: Colourblindness (E)**
- Colourblindness is a sex-linked trait, specifically linked to the X chromosome.
- **Match:** E → (iv) X-chromosome

### Summary of Matches:
- A → (iii) 11th chromosome
- B → (v) 12th chromosome
- C → (ii) 7th chromosome
- D → (i) 4th chromosome
- E → (iv) X-chromosome

### Final Answer:
The correct option from the given codes is:
- A → (iii)
- B → (v)
- C → (ii)
- D → (i)
- E → (iv)