Which of the following is not a tool of genetic engineering ?

Options

A. Clonin vector
B. Restriction enzyme
C. Foreign DNA
D. GMO

Explanation

To determine which of the following is not a tool of genetic engineering, let's analyze each option provided:

1. **Cloning Vector**:
- Cloning vectors are essential tools in genetic engineering. They are DNA molecules used to transport foreign DNA into a host cell. They facilitate the replication of the inserted DNA within the host.

2. **Restriction Enzyme**:
- Restriction enzymes are crucial in genetic engineering as they cut DNA at specific sequences. This allows scientists to manipulate DNA by cutting and pasting different segments together, which is fundamental in the process of creating recombinant DNA.

3. **Foreign DNA**:
- Foreign DNA refers to the DNA that is introduced into a host organism. It is a key component in genetic engineering, as the goal is often to insert new genes into an organism to give it new traits.

4. **GMO (Genetically Modified Organism)**:
- A GMO is an organism that has been altered through genetic engineering. While GMOs are the result of genetic engineering processes, they are not a tool used in the process itself.

Based on this analysis, the answer to the question "Which of the following is not a tool of genetic engineering?" is **GMO**.

### Step-by-Step Solution:
1. **Identify the options**: Cloning vector, restriction enzyme, foreign DNA, GMO.
2. **Define each option**:
- Cloning vector: A tool for transporting foreign DNA.
- Restriction enzyme: A tool for cutting DNA at specific sites.
- Foreign DNA: The DNA that is inserted into the host organism.
- GMO: An organism that has been modified through genetic engineering.
3. **Determine which is not a tool**:
- Cloning vector, restriction enzyme, and foreign DNA are all tools used in genetic engineering.
- GMO is the product of genetic engineering, not a tool.
4. **Conclude**: The option that is not a tool of genetic engineering is **GMO**.