The restrcition enzyme responsible for cleavage of following sequence is
`{:(5'-G-T-Coverset(darr)-G-A-C-3'),(3'-C-A-Gunderset(uarr)-C-T-G-5'):}`

Options

A. (a) EcoRl
B. (b) Hindll
C. (c) BamHl
D. (d) EcoRll

Explanation

To determine the restriction enzyme responsible for cleaving the given sequence, we will analyze the provided DNA sequence and compare it with known restriction enzyme recognition sites.

### Step-by-Step Solution:

1. **Identify the Given Sequence**:
The sequence provided is:
- 5'-G-T-C↓G-A-C-3'
- 3'-C-A-G↑C-T-G-5'
The arrows indicate the cleavage points.

2. **Understand Restriction Enzymes**:
Restriction enzymes are proteins that cut DNA at specific sequences, often palindromic. Each enzyme has a unique recognition site.

3. **List the Options**:
The options provided in the question are:
- A) EcoRI
- B) HindII
- C) BamHI
- D) EcoO109I

4. **Check Each Enzyme's Recognition Site**:
- **EcoRI**: Recognizes the sequence G-A-A-T-T-C and cuts between G and A.
- **HindII**: Recognizes the sequence G-T-C-G-A-C and cuts between G and A, producing sticky ends.
- **BamHI**: Recognizes the sequence G-G-A-T-C-C and cuts between G and G, producing sticky ends.
- **EcoO109I**: Recognizes the sequence C-C-G-G and cuts between G and G, producing sticky ends.

5. **Match the Given Sequence with Recognition Sites**:
- The sequence we have (G-T-C↓G-A-C) matches the recognition site of **HindII** (G-T-C-G-A-C), where it cuts between the G and A.

6. **Conclusion**:
The restriction enzyme responsible for cleaving the provided sequence is **HindII**.

### Final Answer:
The restriction enzyme responsible for cleavage of the given sequence is **HindII**.