pBR322 was the first artificial cloning vector to be constructed. What does "BR" stands for ?

Options

A. 1) Bacteriophage and Recombinant
B. 2) Boliver and Rodriguez
C. 3) Boyer and Replicative
D. 4) None of these

Answer

To answer the question regarding what "BR" stands for in the context of the cloning vector pBR322, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding pBR322**:
- pBR322 is a well-known plasmid that was one of the first artificial cloning vectors created for genetic engineering.

2. **Breaking Down the Name**:
- The name pBR322 can be dissected into its components:
- "p" stands for plasmid.
- "R" and "B" are the letters we need to focus on to determine what they represent.

3. **Identifying the Scientists**:
- The "BR" in pBR322 refers to the names of the two scientists who developed this vector.

4. **Recognizing the Scientists**:
- The correct names associated with "BR" are Bolivar and Rodriguez, who were instrumental in the development of this cloning vector.

5. **Conclusion**:
- Therefore, "BR" stands for Bolivar and Rodriguez.

### Final Answer:
The correct answer is that "BR" stands for Bolivar and Rodriguez.

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