Briefly explain the usea of transgenic animals .

Explanation

Normal physiology and development : Trangenic animals are specifically designed to allow studying about .
How the genes regulated.
How the gene affects normal functioning of body .
How it affects growth and development E.g., insulin like growth factor . The animals are made transgnetic to know the biological effect and result.
Study of disese : Transgenic of disease like cancers , cystic fibrosis , rheumatoid arthritis and Alzheimer.s
Biological products : Transgenic animals are used to produce biological product of human intereset.
`alpha` 1-antitrypsin used to treat emphysema.
Proteins for treatment of PKU and cystic fibrosis.
Trangenic cow , Roise produce human protein enriched milk (2.4 gm/lit.human `alpha` - lactalbumin).
Vaccine safety .
Transgenic mice are being developed and use in testing the safety of vaccines before they are used for humans .
Polio vaccine is tested in mice .
Chemical safety testing .
This is also known as toxicity /safety testing .
Transgenic animals are used to know the effects of toxi chemicals .