Select the disease caused by both hyposecretion as well hypersecretion of a hormone

Options

A. Dwarfism
B. Goitre
C. Acromegaly
D. Diabetes insipidus

Answer

To solve the question of which disease is caused by both hyposecretion and hypersecretion of a hormone, we can follow these steps:

### Step 1: Understand the terms
- **Hyposecretion** refers to the underproduction of a hormone.
- **Hypersecretion** refers to the overproduction of a hormone.

### Step 2: Analyze the options
The options given are:
1. Dwarfism
2. Goiter
3. Acromegaly
4. Diabetes Insipidus

### Step 3: Evaluate each option
- **Dwarfism**: This condition is primarily caused by the hyposecretion of growth hormone. It does not involve hypersecretion.

- **Goiter**: This condition can occur due to both hyposecretion (underproduction) and hypersecretion (overproduction) of thyroid hormones. It is characterized by an enlargement of the thyroid gland.

- **Acromegaly**: This condition is caused by the hypersecretion of growth hormone, usually due to a pituitary tumor. It does not involve hyposecretion.

- **Diabetes Insipidus**: This condition is primarily caused by the hyposecretion of the anti-diuretic hormone (ADH). It does not involve hypersecretion.

### Step 4: Conclusion
From the evaluation, the only condition that can be caused by both hyposecretion and hypersecretion of a hormone is **Goiter**.

### Final Answer:
The disease caused by both hyposecretion and hypersecretion of a hormone is **Goiter**.

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