Which of the following is not a significance of mitosis?

Options

A. Maintenance of cell size
B. Repair of damaged body parts
C. Replacement of skin cells, epidermal cells by the new cells
D. Introduction of variations

Answer

To determine which of the following is not a significance of mitosis, we need to analyze the options provided and understand the roles of mitosis in biological processes.

### Step-by-Step Solution:

1. **Understanding Mitosis**: Mitosis is a type of cell division that results in two daughter cells, each having the same number of chromosomes as the parent cell. It is crucial for growth, development, and tissue repair.

2. **Significance of Mitosis**:
- **Growth and Size Increase**: Mitosis allows organisms to grow by increasing the number of cells. This is essential for the overall growth of an organism.
- **Repair of Damaged Tissues**: When tissues are damaged, mitosis helps in replacing dead or damaged cells, thus aiding in the healing process.
- **Replacement of Epidermal Cells**: Mitosis is responsible for the continuous replacement of skin cells (epidermal cells), ensuring that the skin remains intact and functional.

3. **Identifying the Incorrect Significance**:
- The question asks for the option that is NOT a significance of mitosis.
- It is important to note that while mitosis is involved in growth, repair, and cell replacement, it does not introduce genetic variation. Genetic variation is primarily introduced through meiosis, which is the process of cell division that produces gametes (sperm and eggs).

4. **Conclusion**: Therefore, any option that suggests that mitosis is responsible for introducing variations would be the correct answer to the question.

### Final Answer:
The option that is not a significance of mitosis is the one that states it introduces variations.