Splitting of centromere of each chomosome which was holding sister chromatids together, occurs at

Options

A. Anaphase-I
B. Anaphase-II
C. Telophase-I
D. Telophase-II

Answer

To solve the question regarding the splitting of the centromere of each chromosome that holds sister chromatids together, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Context**: The question pertains to the process of meiosis, which consists of two main divisions: meiosis I and meiosis II.

2. **Identify the Phases of Meiosis**:
- **Meiosis I**: This phase includes prophase I, metaphase I, anaphase I, and telophase I.
- **Meiosis II**: This phase includes prophase II, metaphase II, anaphase II, and telophase II.

3. **Focus on Anaphase**: The question specifically asks about the splitting of the centromere. This occurs during the anaphase stages of meiosis.

4. **Differentiate Between Anaphase I and Anaphase II**:
- In **Anaphase I**, homologous chromosomes are separated, and the centromeres do not split. Instead, the non-sister chromatids are pulled apart.
- In **Anaphase II**, the centromeres of each chromosome split, allowing the sister chromatids to be separated and pulled towards opposite poles of the cell.

5. **Conclusion**: The splitting of the centromere that holds sister chromatids together occurs specifically during **Anaphase II** of meiosis.

### Final Answer:
The splitting of the centromere of each chromosome, which holds sister chromatids together, occurs at **Anaphase II** of meiosis.

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