select the odd one w.r.t disease with prion as causative organisms

Options

A. Scrapie disease in sheep
B. Cholera
C. Creutzfeldt jakob disease
D. Bovine spongiform encephaloathy

Answer

To solve the question of selecting the odd one out with respect to diseases caused by prions, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Prions**: Prions are infectious agents composed mainly of protein. They are known for causing neurodegenerative diseases by inducing misfolding of normal proteins in the brain.

2. **Identify the Options**:
- A. Scrapie's disease in sheep
- B. Cholera
- C. Creutzfeldt-Jakob disease
- D. Bovine spongiform encephalopathy

3. **Analyze Each Option**:
- **Option A: Scrapie's disease in sheep**: This is a prion disease affecting sheep, caused by prions.
- **Option B: Cholera**: This disease is caused by the bacterium Vibrio cholerae, not by prions.
- **Option C: Creutzfeldt-Jakob disease**: This is a human prion disease caused by misfolded prion proteins.
- **Option D: Bovine spongiform encephalopathy (BSE)**: Also known as mad cow disease, this is caused by prions in cattle.

4. **Determine the Odd One Out**:
- From the analysis, options A, C, and D are all diseases caused by prions. However, option B (Cholera) is caused by a bacterium and not by prions.

5. **Conclusion**: The odd one out with respect to diseases caused by prions is **B. Cholera**.

### Final Answer:
**B. Cholera**

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