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Select correct statement w.r.t. thalasse...

Select correct statement w.r.t. thalassemia. (a) It is a recessive autosomal genetic defect. (b) Alpha thalassemia is connected to the deletion of 16p(short arm) chromosome. (c) Beta thalassemia is caused due to mutations in the HBB gene on chromosome 11. (d) About 30% of adult haemoglobin is made up of alpha and delta chains. (e) In beta thalassemia, excess B-chains form unstable tetramers which have abnormal oxygen dissociation curve.

A

(b), (c) & (d)

B

(a), (b) & (e)

C

All except (b) & (e)

D

All except (d) & (e)

Text Solution

Verified by Experts

The correct Answer is:
D
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