Which of the following is a correct match between disease and its respective cause

Options

A. Gout- Deposition of urea in synovial joints
B. Rheumatoid arthritis - Deficiency of dystrophin protein
C. Osteoporosis - Imbalance between calcitonin and parathyroid hormone levels
D. Rickets - Autoimmune disorder

Answer

To determine the correct match between diseases and their respective causes, let's analyze each option step by step:

1. **Gout**:
- The statement claims that gout is caused by the deposition of urea in synovial joints.
- **Analysis**: Gout is actually caused by the accumulation of uric acid, not urea. When uric acid levels in the blood become too high, it can form crystals that deposit in the joints, leading to inflammation and pain.
- **Conclusion**: This match is incorrect.

2. **Rheumatoid Arthritis**:
- The statement claims that rheumatoid arthritis is due to a deficiency of dystrophin protein.
- **Analysis**: Rheumatoid arthritis is an autoimmune disease where the immune system mistakenly attacks the joints. Dystrophin is related to muscular dystrophy, not rheumatoid arthritis.
- **Conclusion**: This match is incorrect.

3. **Osteoporosis**:
- The statement claims that osteoporosis is caused by an imbalance between calcitonin and parathyroid hormone levels.
- **Analysis**: Osteoporosis occurs when there is a decrease in bone density, often due to hormonal changes. Calcitonin helps lower blood calcium levels, while parathyroid hormone increases it. An imbalance in these hormones can lead to weakened bones, making this match correct.
- **Conclusion**: This match is correct.

4. **Rickets**:
- The statement claims that rickets is an autoimmune disease.
- **Analysis**: Rickets is actually caused by a deficiency of vitamin D, which is essential for calcium absorption in bones. It is not an autoimmune disease.
- **Conclusion**: This match is incorrect.

**Final Answer**: The correct match between disease and its respective cause is **Osteoporosis** (option 3).