Secretion from which of the following cells inhibits the development of paramesonephric duct in males?

Options

A. Interstitial cells
B. Sertoli cells
C. Spermatogonia
D. Spermatozoa

Answer

To solve the question regarding which cells inhibit the development of the paramesonephric duct in males, we can follow these steps:

### Step-by-Step Solution:

1. **Understanding the Paramesonephric Duct**:
- The paramesonephric duct, also known as the Müllerian duct, is a structure present in the early stages of embryonic development. In females, it develops into the fallopian tubes, uterus, and part of the vagina. In males, this duct typically degenerates.

2. **Identifying the Role of Sertoli Cells**:
- Sertoli cells are specialized cells located in the testes. They play a crucial role in supporting and nurturing developing sperm cells. Importantly, Sertoli cells are responsible for producing the Anti-Müllerian Hormone (AMH).

3. **Function of Anti-Müllerian Hormone (AMH)**:
- AMH is a hormone that inhibits the development of the paramesonephric duct in males. When AMH is secreted, it causes the paramesonephric duct to degenerate, preventing the formation of female reproductive structures.

4. **Conclusion**:
- Since the question asks which cells inhibit the development of the paramesonephric duct in males, the answer is Sertoli cells, as they secrete AMH which leads to the degeneration of this duct.

### Final Answer:
The secretion from Sertoli cells inhibits the development of the paramesonephric duct in males.

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