During an allergic reaction, histamine is released into blood by

Options

A. Eosinophils
B. Basophils
C. `I_gE`
D. Neutrophils

Answer

To answer the question "During an allergic reaction, histamine is released into the blood by," we will analyze the options provided and determine which cell is responsible for the release of histamine during an allergic reaction.

### Step-by-Step Solution:

1. **Understanding Histamine**:
- Histamine is a chemical that plays a central role as a mediator in allergic reactions and inflammatory responses. It is released by certain cells in the body during these reactions.

**Hint**: Histamine is crucial in the body's response to allergens.

2. **Analyzing the Options**:
- **Eosinophils**: These are white blood cells that primarily deal with parasitic infections and modulate inflammatory responses. However, they do not release histamine.

**Hint**: Eosinophils are involved in inflammation but do not release histamine.

- **Basophils**: These cells are known to release histamine and other chemicals during allergic reactions. They play a significant role in mediating allergic responses.

**Hint**: Basophils are the key players in releasing histamine during allergies.

- **IgE**: This is an immunoglobulin (antibody) that provides protection against parasitic infections and is involved in allergic reactions, but it is not a cell that releases histamine.

**Hint**: IgE is an antibody, not a cell.

- **Neutrophils**: These are phagocytic cells that engulf and digest foreign materials but do not release histamine.

**Hint**: Neutrophils are important for fighting infections but do not release histamine.

3. **Conclusion**:
- Based on the analysis of the options, the correct answer is **Basophils**. They are the cells that release histamine into the blood during an allergic reaction.

**Final Answer**: Basophils