Maturation and differentiation of T-cells occurs in

Options

A. Bone marrow
B. Thyroid
C. Thymus
D. Secondary lymphoid organs

Answer

To solve the question regarding where the maturation and differentiation of T-cells occurs, we can follow these steps:

### Step-by-Step Solution:

1. **Understand the Question**: The question asks where T-cells mature and differentiate. T-cells are a type of white blood cell that plays a crucial role in the immune response.

2. **Identify the Options**: The options provided are:
- A) B-cells
- B) Thyroid
- C) Thymus
- D) Secondary lymphoid organs

3. **Analyze Each Option**:
- **A) B-cells**: This option is incorrect because B-cells mature in the bone marrow, not in the thymus.
- **B) Thyroid**: This option is also incorrect. The thyroid gland is an endocrine gland that produces hormones regulating metabolism, and it is not involved in T-cell maturation.
- **C) Thymus**: This option is correct. The thymus is the primary site for T-cell maturation and differentiation. T-cells originate from bone marrow but migrate to the thymus to mature.
- **D) Secondary lymphoid organs**: While T-cells can be activated in secondary lymphoid organs (like lymph nodes and the spleen), they do not mature there.

4. **Conclusion**: Based on the analysis, the correct answer is **C) Thymus**.

### Final Answer:
The maturation and differentiation of T-cells occurs in the **Thymus**.

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