First clinical gene therapy was conducted in

Options

A. 1983
B. 1997
C. 1890
D. 1990

Answer

**Step-by-Step Solution:**

1. **Understanding Gene Therapy**: Gene therapy is a medical technique that involves altering the genes inside a person's cells to treat or prevent disease. It aims to correct faulty genes responsible for disease development.

2. **Identifying the First Clinical Gene Therapy**: The question specifically asks for the first clinical gene therapy conducted. This refers to the first approved instance where gene therapy was applied in a clinical setting.

3. **Date and Year of the First Clinical Gene Therapy**: The first clinical gene therapy was conducted on September 14, 1990. This is a crucial detail as it marks the beginning of gene therapy in a clinical context.

4. **Location of the Procedure**: The procedure was performed at the National Institutes of Health (NIH) in the United States. This institution is known for its significant contributions to medical research.

5. **Patient Details**: The first patient to receive this gene therapy was a 4-year-old child suffering from severe combined immunodeficiency (SCID), also known as "bubble boy" disease. This condition is caused by genetic mutations that result in a severely compromised immune system.

6. **Outcome of the Therapy**: The gene therapy successfully treated the child's immune deficiency, showcasing the potential of gene therapy to cure genetic disorders.

7. **Conclusion**: Therefore, the first clinical gene therapy was conducted on September 14, 1990, at the National Institutes of Health, and it involved a 4-year-old child with severe immune deficiency.

**Final Answer**: The first clinical gene therapy was conducted on September 14, 1990.

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