The disease associated with prions

Options

A. kuru (laughing death)
B. mad cow disease and scrapie of goat and sheep
C. Creutzfeldt Jakob disease (CJD) of man
D. all of the above

Answer

**Step-by-Step Solution:**

1. **Understanding Prions**: Prions are misfolded proteins that can induce other normal proteins in the brain to also misfold. This leads to neurodegenerative diseases.

2. **Identifying Diseases Associated with Prions**:
- **Kuru**: This is a disease associated with prions, primarily found in humans who have consumed contaminated human brain tissue.
- **Mad Cow Disease (Bovine Spongiform Encephalopathy)**: This is a prion disease that affects cattle and can be transmitted to humans through consumption of infected beef.
- **Scrapie**: This is a prion disease that affects sheep and goats, causing similar neurodegenerative effects.
- **Creutzfeldt-Jakob Disease (CJD)**: This is a neurodegenerative disorder in humans caused by prions, leading to rapid cognitive decline and other neurological symptoms.

3. **Evaluating the Options**:
- Option 1: Kuru is a prion disease.
- Option 2: Mad Cow Disease and Scrapie are also prion diseases.
- Option 3: Creutzfeldt-Jakob Disease is a prion disease as well.
- Option 4: Since all the diseases listed in the previous options are associated with prions, this option is correct.

4. **Conclusion**: The correct answer is option 4, "all of the above," as all listed diseases are associated with prions.

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