Trypanosoma gambiense is found in

Options

A. large intestine
B. liver
C. blood
D. blood and cerebrospinal fluid

Answer

**Step-by-Step Solution:**

1. **Identify the Organism**: The question asks about Trypanosoma gambiense, which is a unicellular eukaryotic organism and a known parasite.

2. **Understand the Vector**: Trypanosoma gambiense is transmitted by the tsetse fly. This is an important detail as it indicates where the parasite originates from.

3. **Infection Process**: When the tsetse fly bites a human, it injects metacyclic trypomastigotes, which are the infective forms of Trypanosoma gambiense.

4. **Location in the Host**: Once inside the human body, these metacyclic trypomastigotes enter the bloodstream and can spread throughout the body, including the lymphatic system and the cerebrospinal fluid.

5. **Multiplication**: In the blood, the metacyclic trypomastigotes transform into trypomastigotes and multiply. This multiplication occurs in the blood and can also affect the central nervous system (CNS).

6. **Disease Caused**: The presence of Trypanosoma gambiense in the CNS leads to a condition known as sleeping sickness, which is characterized by neurological symptoms.

7. **Conclusion**: Therefore, Trypanosoma gambiense is primarily found in the blood and cerebrospinal fluid of infected individuals.

**Final Answer**: Trypanosoma gambiense is found in the blood and cerebrospinal fluid.

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