A person suffering from a disease caused by Plasmodium, experiences recurring chill and fever at the time when

Options

A. The sporozoites released from RBCs are being rapidly killed and broken down inside spleen
B. The trophozoites reach maximum growth and give out certain toxins
C. The parasite after its rapid multiplication inside RBCs ruptures them, releasng the stage to enter fresh RBCs
D. The microgametocytes and megaga- metocytes are being destroyed by the WBCs

Answer

**Step-by-Step Solution:**

1. **Understanding the Disease**: The disease caused by Plasmodium is known as malaria. It is transmitted through the bite of an infected female Anopheles mosquito.

2. **Life Cycle of Plasmodium**: The Plasmodium parasite has a complex life cycle that includes several stages:
- The mosquito injects sporozoites into the human bloodstream.
- These sporozoites travel to the liver and develop into schizonts.
- The schizonts rupture, releasing merozoites into the bloodstream.

3. **Infection of Red Blood Cells (RBCs)**: The merozoites invade red blood cells, where they multiply. This multiplication leads to the destruction of the RBCs.

4. **Release of Toxins**: When the merozoites multiply and eventually rupture the RBCs, they release toxins into the bloodstream.

5. **Symptoms of Malaria**: The release of these toxins is what causes the characteristic symptoms of malaria, including recurring chills and fever. This occurs because the immune system reacts to the toxins released during the rupture of the RBCs.

6. **Conclusion**: Therefore, a person suffering from malaria experiences recurring chills and fever at the time when the merozoites, after their rapid multiplication inside the RBCs, rupture them and release toxins.

**Final Answer**: The correct option is C: "The parasite after its rapid multiplication inside RBCs ruptures them releasing the stage into fresh RBCs."

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