Shape of chromosome can be best observed during

Options

A. Metaphase
B. Anaphase
C. Telophase
D. Late prophase

Answer

### Step-by-Step Solution:

1. **Understanding Chromosomes**: Chromosomes are structures that carry genetic material. They are made up of DNA and proteins and are essential for cell division.

2. **Identifying the Stages of Cell Division**: The cell division process includes several stages: prophase, metaphase, anaphase, and telophase. Each stage has distinct characteristics.

3. **Analyzing Each Stage**:
- **Prophase**: During prophase, chromosomes begin to condense, but they can appear tangled or overlapped, making it difficult to clearly observe their shape.
- **Metaphase**: In metaphase, chromosomes are fully condensed and aligned at the cell's equatorial plane. This stage allows for the best visibility of the distinct shapes of chromosomes, including their centromeres and chromatids.
- **Anaphase**: During anaphase, sister chromatids are pulled apart towards opposite poles of the cell. The separation makes it challenging to observe the distinct shape of individual chromosomes.
- **Telophase**: In telophase, chromosomes reach the poles and begin to de-condense. They are less distinct and not easily observable in their characteristic shapes.

4. **Conclusion**: The best stage to observe the shape of chromosomes is during **metaphase** because they are highly condensed and clearly visible, allowing for easy differentiation of their structures.

### Final Answer:
The shape of chromosomes can be best observed during **metaphase**.

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