Centriole replicates during

Options

A. Metaphase
B. Late prophase
C. `G_(1)` of I phase
D. S-phase of I phase

Answer

**Step-by-Step Solution:**

1. **Understanding the Question:** The question asks during which phase the centriole replicates. The options provided are metaphase, late prophase, G1 of interphase, and S-phase of interphase.

2. **Identifying Interphase Stages:** Interphase is divided into three main stages: G1 (Gap 1), S (Synthesis), and G2 (Gap 2). Each of these stages has specific activities occurring within the cell.

3. **Activities in Each Interphase Stage:**
- **G1 Phase:** This phase involves cell growth and an increase in cell size. There is no DNA or centriole replication during this phase.
- **S Phase:** This is the critical phase for DNA replication, where the cell synthesizes a complete copy of the DNA in its nucleus. Importantly, this is also when centriole replication occurs.
- **G2 Phase:** This phase involves further growth and preparation for cell division, including protein and RNA synthesis, but centriole replication has already occurred.

4. **Understanding Mitosis Phases:** After interphase, the cell enters mitosis, which includes prophase, metaphase, anaphase, and telophase. During these phases, the focus is on the separation and distribution of chromosomes, not on the replication of organelles like centrioles.

5. **Conclusion:** Since centriole replication occurs during the S-phase of interphase, the correct answer to the question is the S-phase of interphase.

**Final Answer:** The centriole replicates during the S-phase of interphase.

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