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Nucleolus disappears in...

Nucleolus disappears in

A

late prophase

B

metaphase

C

early prophase

D

interphase

Text Solution

AI Generated Solution

The correct Answer is:
### Step-by-Step Solution: 1. **Understanding the Cell Cycle**: The cell cycle consists of several phases, including interphase (G1, S, G2) and the mitotic phase (M phase), which includes prophase, metaphase, anaphase, and telophase. 2. **Identifying the Stages of Mitosis**: During the M phase, mitosis occurs, which is divided into several stages: prophase, metaphase, anaphase, and telophase. 3. **Focusing on Prophase**: Prophase is further divided into three stages: early prophase, middle prophase, and late prophase. 4. **Events in Early Prophase**: In early prophase, chromosomes begin to condense from a diffuse state into a more compact form. 5. **Events in Middle Prophase**: During middle prophase, the chromosomes become shorter and thicker, and they occupy the central space of the nucleus. The nucleolus is still present and may attach to the chromosomes. 6. **Events in Late Prophase**: It is in late prophase that significant changes occur. The nucleolus disappears, and the nuclear membrane begins to break down. This marks the transition to metaphase. 7. **Conclusion**: The nucleolus disappears specifically during the late prophase stage of mitosis. ### Final Answer: The nucleolus disappears in **late prophase**. ---
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