Identify the meiotic stage in which the homologous chromosomes separate while the sister chromatids remain associated at their centrometres. Or In which stage of meiosis homologous chromosomes are segregated

Options

A. Anaphase I
B. Anaphase II
C. Metaphase I
D. Metaphase II

Answer

To identify the meiotic stage in which homologous chromosomes separate while the sister chromatids remain associated at their centromeres, we can follow these steps:

### Step-by-Step Solution:

1. **Understand Meiosis**: Meiosis is a type of cell division that reduces the chromosome number by half, resulting in four daughter cells, each with half the number of chromosomes of the parent cell. It consists of two main stages: Meiosis I and Meiosis II.

2. **Identify the Stages of Meiosis**:
- **Meiosis I**: This includes Prophase I, Metaphase I, Anaphase I, and Telophase I.
- **Meiosis II**: This includes Prophase II, Metaphase II, Anaphase II, and Telophase II.

3. **Focus on Anaphase I**: In Anaphase I, homologous chromosomes (each consisting of two sister chromatids) are pulled apart and segregated to opposite poles of the cell. However, the sister chromatids remain attached at their centromeres.

4. **Clarify the Role of Sister Chromatids**: It is important to note that during Anaphase I, while the homologous chromosomes separate, the sister chromatids do not separate until Anaphase II.

5. **Conclusion**: Therefore, the meiotic stage where homologous chromosomes separate while the sister chromatids remain associated at their centromeres is **Anaphase I**.

### Final Answer:
The meiotic stage in which homologous chromosomes separate while the sister chromatids remain associated at their centromeres is **Anaphase I**.

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