Which has both Fe and Cu as prosthetic group?

Options

A. Haemoglobin
B. Dehydrogenase
C. Polymerase
D. Cytochrome oxidase

Answer

To determine which of the given options has both iron (Fe) and copper (Cu) as prosthetic groups, we can analyze each option one by one.

### Step-by-Step Solution:

1. **Understanding Prosthetic Groups**:
- Prosthetic groups are tightly bound non-polypeptide units that are essential for the biological function of proteins. They can be organic or inorganic in nature.

**Hint**: Remember that prosthetic groups can be metal ions (inorganic) or other molecules (organic).

2. **Analyzing Each Option**:
- **Hemoglobin**: This protein contains iron (Fe) as its prosthetic group but does not contain copper (Cu). It is primarily responsible for oxygen transport in the blood.

**Hint**: Hemoglobin is known for its iron content, which is crucial for its function.

- **Dehydrogenase**: This enzyme typically contains copper (Cu) as a prosthetic group but does not have iron (Fe). It plays a role in oxidation-reduction reactions.

**Hint**: Dehydrogenases are often associated with redox reactions and may contain copper.

- **Polymerase**: This enzyme does not have any prosthetic groups associated with it. It is involved in the synthesis of nucleic acids.

**Hint**: Polymerases are primarily involved in DNA and RNA synthesis without needing prosthetic groups.

- **Cytochrome Oxidase**: This enzyme contains both iron (Fe) and copper (Cu) as prosthetic groups. It is a part of the electron transport chain and is involved in the transfer of electrons to oxygen.

**Hint**: Cytochrome oxidase is crucial for cellular respiration and contains both metal ions.

3. **Conclusion**:
- The only option that contains both iron and copper as prosthetic groups is **Cytochrome Oxidase**.

### Final Answer:
**Cytochrome Oxidase** has both Fe and Cu as prosthetic groups.