Bursa of Fabricius is an important organ of birds. This organ is associated with

Options

A. generation of basophils
B. production of uric acid
C. metabolism of fatty acids
D. generation of B-cell

Answer

**Step-by-Step Solution:**

1. **Understanding the Bursa of Fabricius**: The Bursa of Fabricius is a specialized organ found in birds. It plays a crucial role in the immune system of these animals.

2. **Location**: This organ is located in the cloaca of birds. The cloaca is a common cavity at the end of the digestive tract that serves as the only opening for the intestinal, reproductive, and urinary tracts.

3. **Function**: The primary function of the Bursa of Fabricius is related to the immune system. It is essential for the development of B-cells, which are a type of white blood cell important for the adaptive immune response.

4. **Hematopoiesis**: The Bursa of Fabricius is also recognized as a site of hematopoiesis, which is the process of forming blood cellular components. In birds, this organ is crucial for the maturation of B-cells.

5. **Answering the Question**: Among the given options:
- A) Generation of basophils: Incorrect, as basophils are not produced in the Bursa of Fabricius.
- B) Production of uric acid: Incorrect, as uric acid production is related to the excretory system, not the Bursa.
- C) Metabolism of fatty acids: Incorrect, as this function is not associated with the Bursa.
- D) Generation of B-cells: Correct, as the Bursa of Fabricius is specifically involved in the generation and maturation of B-cells.

6. **Conclusion**: Therefore, the Bursa of Fabricius is associated with the generation of B-cells, making the correct answer option D.

**Final Answer**: The Bursa of Fabricius is associated with the generation of B-cells (Option D).

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